ISSN 1662-4009 (online)

ey0016.11-8 | Metabolic Signaling | ESPEYB16

11.8. An endothelial-to-adipocyte extracellular vesicle axis governed by metabolic state

C Crewe , N Joffin , JM Rutkowski , M Kim , F Zhang , DA Towler , R Gordillo , PE Scherer

To read the full abstract: Cell. 2018; 175(3): 695–708This paper demonstrates for the first time the existence of extracellular vesicle (EV)-mediated signaling between cell types within the adipose tissue. The results of various experiments show a network of EV-mediated exchange of cellular material in adipose tissue. This newly discovered EV trafficking in adipose tissue...